hGH -SENSITIVE ELISA
480€ (96 det.)
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Name
hGH -SENSITIVE ELISA
Category
ELISA Kits
Provider
Mediagnost
Reference
E022
Tested Applications
Elisa
Description
The ELISA E022 is intended to be used for quantitative measurement of human growth hormone in human serum and plasma samples.
Descripción
El Kit E022 está diseñado para la medición cuantitativa de la hormona de crecimiento humana en muestras de suero y plasma humanos.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Assay Data | Reference Material: NIBSC 98/574 Incubation Period: 3.25 h Calibrator: recombinant growth hormone Control: 1 control , freeze-dried |
| Test Range | 0.0115 – 26 µg/L |
| Sensitivity | 0.0115 µg/L |
| Recommended Dilution | 1:26 |
| Origin | Antibody: Rabbit |
| Size 1 | 96 det. |
| Tested Applications | Elisa |
| Sample Type | Serum EDTA / Heparin Plasma |
| Availability | 3-5 days. |
| Storage | Shelf life: between 1 and 2 years. Inquire about availability Store the kit at 2-8°C after receipt until its expiry date |
| Alias | Growth hormone,GH, somatotropin |
| Background | Elisa Kits for: GH1 |
| Status | IVD |
| Note | Intra/Interassay Variance [%]< 10 |
Background
The endocrine system of human Growth Hormone (hGH), also named Somatropin, is characterized by an extreme complexity. hGH is the product of the GH-1 gene located on chromosome 17 and expressed in pituitary cells. 80% of the hGH is a non-glycolsylated 22 kDa protein consisting of 191 amino acids. About 20% is a variant form of 20 kDa resulting from alternative splicing. Additionally, several smaller variants can be found in circulation as well as translational modificated proteins and different degrees of protein aggregation. Bioactivity of Growth Hormone is regulated by a specific binding protein (GHBP) formed by the extra cellular part of the cellular transmembran GH-receptor. These modifications allow a tight control of the half-life period hGH and of its bioactivity.
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