Human Lysophosphatidylserine lipase ABHD12 (ABHD12) ELISA Kit

715€ (96 tests)
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name
Human Lysophosphatidylserine lipase ABHD12 (ABHD12) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx384535
tested applications
ELISA
Description
Human Lysophosphatidylserine lipase ABHD12 (ABHD12) ELISA Kit is an ELISA kit against Human Monoacylglycerol lipase ABHD12 (ABHD12).
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Lysophosphatidylserine lipase ABHD12 (ABHD12) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.17 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8N2K0 |
| Gene ID | 26090 |
| OMIM | 612674 |
| Alias | ABHD12A,BEM46L2,C20orf22,PHARC |
| Background | Elisa Kits for: ABHD12 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
ABHD12 (Abhydrolase Domain Containing 12) is a membrane-bound serine hydrolase primarily involved in lipid metabolism and neuroinflammatory regulation. It plays a critical role in degrading lysophosphatidylserine (lyso-PS), a bioactive lipid mediator involved in immune signaling. ABHD12 is highly expressed in the brain and other tissues, where it regulates lipid signaling pathways crucial for neural function and homeostasis. Mutations in the ABHD12 gene are associated with PHARC syndrome (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataracts), a neurodegenerative disorder. This enzyme’s activity is essential for maintaining balanced lipid signaling and protecting against neuroinflammation and neurodegeneration.
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