Human Natural Cytotoxicity Triggering Receptor 3 (NCR3) ELISA Kit
689€ (96 tests)
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935106861
info@markelab.com
name
Human Natural Cytotoxicity Triggering Receptor 3 (NCR3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx257677
tested applications
ELISA
Description
Human Natural Cytotoxicity Triggering Receptor 3 (NCR3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human NKp30/NCR3 concentrations in cell culture supernatants, tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Natural Cytotoxicity Triggering Receptor 3 (NCR3) |
| Reactivity | Human |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 15.6 pg/ml - 1000 pg/ml |
| Sensitivity | < 6.2 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Cell culture supernatants, tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O14931 |
| Gene ID | 259197 |
| Alias | Activating natural killer receptor p30,1C7,MALS,CD337,LY117,NKp30,Natural killer cell p30-related protein |
| Background | Elisa Kits for: NCR3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
Natural Cytotoxicity Triggering Receptor 3 (NCR3), also known as NKp30, is a critical receptor for natural killer (NK) cell activation and functions as part of the body’s innate immune response. NK cells are lymphocytes specialized in identifying and killing abnormal cells, such as those infected by viruses or transformed into cancer cells. Unlike T cells and B cells, which rely on antigen specificity, NK cells use a variety of activating receptors, including NCR3, to recognize stressed or infected cells. NCR3, part of the NCR family (alongside NCR1 and NCR2), plays a vital role in immune surveillance by mediating NK cell cytotoxicity and cytokine production in response to cellular stress signals. NCR3’s activation allows NK cells to promptly respond to potential threats without prior sensitization. NCR3 is distinct among the NCRs in its broader expression across both innate and adaptive immune cells, and its activity has been shown to influence adaptive immunity. NCR3 is found not only on NK cells but also on certain subtypes of T cells and other immune cells in specific conditions, amplifying its potential for immune modulation.
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