Human ADAMTS-Like Protein 1 (ADAMTSL1) Protein
624€ (20 µg)
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935106861
info@markelab.com
name
Human ADAMTS-Like Protein 1 (ADAMTSL1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx692492
tested applications
SDS-PAGE
Description
Adamts-Like Protein 1 (ADAMTSL1) protein is a recombinant Human protein expressed in Insect.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Adamts-Like Protein 1 (ADAMTSL1) |
| Host | Insect |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-His439 Tag: C-terminal His tag |
| Origin | Human |
| Observed MW | 47 kDa |
| Expression | Recombinant |
| Purity | > 97% (SDS-PAGE) |
| Size 1 | 20 µg |
| Size 2 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: Sterile 20 mM Tris, 500 mM NaCl, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | Q8N6G6-2 |
| Alias | Punctin-1,ADAMTSL-1 |
| Background | Protein ADAMTSL1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
ADAMTSL1 is a member of the ADAMTS-like (ADAMTSL) protein family, which is structurally related to the ADAMTS proteases but lacks catalytic activity due to the absence of the metalloproteinase domain. ADAMTSL1 is characterized by thrombospondin type 1 repeats (TSRs) and cysteine-rich domains. It is primarily involved in the assembly and regulation of extracellular matrix (ECM) components, particularly fibrillin microfibrils, which are crucial for maintaining tissue integrity and elasticity. Dysregulation of ADAMTSL1 has been associated with connective tissue disorders and ECM-related diseases. Research suggests that ADAMTSL1 may modulate transforming growth factor-beta (TGF-β) signaling pathways, which play essential roles in cellular proliferation and differentiation.
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