Human Pituitary Adenylate Cyclase-Activating Polypeptide Type I Receptor (ADCYAP1R1) Protein
1118€ (50 µg)
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935106861
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name
Human Pituitary Adenylate Cyclase-Activating Polypeptide Type I Receptor (ADCYAP1R1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691160
tested applications
SDS-PAGE
Description
Pituitary Adenylate Cyclase-Activating Polypeptide Type I Receptor (ADCYAP1R1) protein is a recombinant Human protein expressed in HEK293 cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Pituitary Adenylate Cyclase-Activating Polypeptide Type I Receptor (ADCYAP1R1) |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Ala155 Tag: C-terminal Fc tag |
| Origin | Human |
| Observed MW | 42 kDa |
| Expression | Recombinant |
| Purity | > 88% (SDS-PAGE) |
| Size 1 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: Sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | P41586 |
| Gene ID | 117 |
| OMIM | 102981 |
| Alias | ADCYAP1R1,PAC1R,PVR1,PACAP receptor 1,PACAP type IA receptor,PACAPR1,pituitary adenylate cyclase activating polypeptide 1 receptor,PACAP1-R,adenylate cyclase activating polypeptide 1 receptor 1,adenylate cyclase activating polypeptide 1 receptor type 1,ADCYAP receptor type 1,PAC1,PACAPR, PACAPRI |
| Background | Protein ADCYAP1R1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
The ADCYAP1R1 gene encodes the PAC1 receptor, which belongs to the class B G-protein-coupled receptor (GPCR) family. This receptor is the primary target of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP), a neuropeptide that regulates various physiological processes. ADCYAP1R1 is widely expressed in the central nervous system (CNS), endocrine glands, and peripheral tissues. Upon PACAP binding, it activates adenylyl cyclase and stimulates the production of cyclic AMP (cAMP), leading to downstream signal transduction. ADCYAP1R1 plays critical roles in neuroprotection, stress response, metabolism, and immune regulation. Dysregulation of this receptor has been linked to neurological disorders, anxiety, depression, and inflammatory diseases, underscoring its importance in maintaining physiological homeostasis.
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