Human AF4/FMR2 Family, Member 1 (AFF1) Protein

234€ (10 µg)
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935106861
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name
Human AF4/FMR2 Family, Member 1 (AFF1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166951
tested applications
WB, SDS-PAGE
Description
Human AFF1 Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | AF4/FMR2 Family, Member 1 (AFF1) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Gly183 Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 24.2 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| Alias | AF4,FEL,MLLT2,PBM1 |
| Background | Protein AFF1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
The AFF (AF4/FMR2) family member refers to a group of proteins associated with various cellular functions, particularly in the context of gene regulation and transcriptional control. The name "AFF" comes from the fusion partner of MLL (Mixed-Lineage Leukemia) in certain leukemia cases, where AFF1, also known as AF4, is one of the fusion partners. AFF1 (AF4) is a protein implicated in chromosomal translocations that result in acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). It's known to be involved in transcriptional elongation and regulation. The AF4 protein itself is associated with the super elongation complex (SEC), which plays a role in regulating RNA polymerase II elongation.
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