Human Apolipoprotein F (APOF) ELISA Kit

Este producto es parte de APOF - Apolipoprotein F
Human Apolipoprotein F (APOF) ELISA Kit
611€ (96 tests)

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Name
Human Apolipoprotein F (APOF) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx252036
Tested Applications
ELISA

Description

Human Apolipoprotein F (APOF) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Apolipoprotein F concentrations in serum, plasma and other biological fluids.

Documentos del producto

Instrucciones
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Data sheet
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Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Apolipoprotein F (APOF)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.78 ng/ml - 50 ng/ml
Sensitivity
0.47 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q13790
Alias
APOF, Apo-F, LTIP, apolipoprotein F,Apo F
Background
Elisa Kits for: APOF
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

Apolipoprotein F (APOF) is a lesser-known but essential component of the apolipoprotein family, predominantly found in high-density lipoproteins (HDL) and low-density lipoproteins (LDL). ApoF plays a regulatory role in cholesteryl ester transfer protein (CETP) activity, which facilitates the transfer of cholesteryl esters from HDL to triglyceride-rich lipoproteins like VLDL and LDL. By modulating CETP activity, ApoF influences cholesterol distribution, lipid metabolism, and the balance between HDL and LDL particles. ApoF is mainly synthesized in the liver and circulates in plasma, with elevated levels observed in dyslipidemia and cardiovascular diseases. ApoF is thought to act as a negative regulator of CETP, reducing cholesterol transfer and preserving HDL levels, which are vital for reverse cholesterol transport and cardiovascular health. Its role in maintaining HDL function positions ApoF as a potential therapeutic target in atherosclerosis and other metabolic disorders. Further research is exploring its contribution to lipid homeostasis, inflammation, and cholesterol efflux pathways, which are critical for combating cardiovascular disease and lipid-related pathologies.

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