Human Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Protein
208€ (10 µg)
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935106861
info@markelab.com
name
Human Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx652708
tested applications
WB, SDS-PAGE
Description
Human Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Brain Specific Angiogenesis Inhibitor 1 / BAI1 (ADGRB1) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Ala31-Pro350 Tag: N-terminal His tag and GST tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 64.1 kDa Observed MW (SDS-PAGE): 64 kDa |
| Expression | Recombinant |
| Purity | > 80% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| Alias | ADGRB1,BAI1,GDAIF |
| Background | Protein ADGRB1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in ddH2O to a concentration between 0.1-0.2 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 50 µg/ml |
Descripción
ADGRB1, also known as BAI1 (Brain-Specific Angiogenesis Inhibitor 1), is a member of the adhesion G protein-coupled receptor (GPCR) family predominantly expressed in the brain. It plays a critical role in inhibiting angiogenesis, promoting synaptic plasticity, and mediating phagocytic clearance of apoptotic cells and pathogens. Structurally, ADGRB1 contains multiple extracellular domains that facilitate interactions with matrix proteins and apoptotic cell markers. Dysregulation of ADGRB1 is associated with glioblastoma, as it suppresses tumor angiogenesis and growth, and its loss can contribute to tumor progression. Additionally, it has been implicated in synaptic function and neuronal health, with potential roles in neurodevelopmental disorders and neurodegeneration. ADGRB1’s ability to link extracellular signals to intracellular pathways highlights its importance in vascular regulation and brain function.
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