Human Dipeptidyl Peptidase 4 (DPP4) Protein

Este producto es parte de DPP4 - dipeptidyl peptidase 4
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546€ (100 µg)

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935106861
info@markelab.com
name
Human Dipeptidyl Peptidase 4 (DPP4) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx620383
tested applications
ELISA, WB, SDS-PAGE

Description

Human Dipeptidyl Peptidase 4 (DPP4) Protein is a recombinant Human protein produced in a Mammalian cell expression system.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Dipeptidyl Peptidase 4 (DPP4)
Host
Mammalian cells
Assay Type
Activity: Not tested
Sequence Fragment: Asn29-Pro766
Tag: C-terminal His tag
Origin
Human
Conjugation
Unconjugated
Observed MW
Calculated MW: 88.02 kDa
Expression
Recombinant
Purity
> 90% (SDS-PAGE)
Size 1
100 µg
Size 2
1 mg
Form
Lyophilized
Tested Applications
ELISA, WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20 °C to 80°C. Avoid repeated freeze-thaw cycles.
Shelf Life: 12 months.
Dry Ice
No
UniProt ID
P27487
Alias
CD26,ADABP,ADCP2,DPPIV,TP103,Dipeptidyl peptidase 4,Adenosine deaminase complexing protein 2,ADCP-2,Dipeptidyl peptidase IV,T-cell activation antigen CD26
Background
Protein DPP4
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Reconstitute in sterile water to produce a stock solution.

Descripción

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Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor(TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix(ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

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