Human Docking Protein 4 (DOK4) ELISA Kit

Este producto es parte de DOK - Docking protein
Human Docking Protein 4 (DOK4) ELISA Kit
715€ (96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

Name
Human Docking Protein 4 (DOK4) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx386970
Tested Applications
ELISA

Description

Human Docking Protein 4 (DOK4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DOK4 concentrations in serum, plasma and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Docking Protein 4 (DOK4)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.313 ng/ml - 20 ng/ml
Sensitivity
< 0.188 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma and other biological fluids.
Availability
Shipped within 5-12 working days.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q8TEW6
Gene ID
55715
OMIM
608333
Alias
Downstream of tyrosine kinase 4,Insulin receptor substrate 5,IRS-5,IRS5
Background
Elisa Kits for: DOK4
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

DOK4 is an adaptor protein belonging to the DOK family, involved in signal transduction downstream of receptor tyrosine kinases, such as RET and insulin receptors. It modulates pathways like MAPK/ERK and PI3K/Akt, influencing cellular proliferation, survival, and differentiation. DOK4 is expressed in tissues like skeletal muscle, adipose tissue, and the nervous system, where it regulates metabolic signaling and cellular responses. It acts as a negative regulator of signaling by binding to SH2 domains and inhibiting downstream activation. Dysregulation of DOK4 is associated with metabolic disorders, insulin resistance, and certain cancers, where it influences cell adhesion and motility.

Productos relacionados

abx000611

Docking Protein 4 (DOK4) Antibody

DOK4 Antibody is a Rabbit Polyclonal antibody against DOK4. The downstream of kinase family (Dok-1-7) are members of a c…

Ver producto
abx013720

Docking Protein 4 (DOK4) Antibody

Rabbit polyclonal antibody against DOK4 protein. Immunogen region is N-terminal.…

Ver producto
abx033623

Docking Protein 4 (DOK4) Antibody

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, on…

Ver producto