Human E3 Ubiquitin-Protein Ligase CBL-C (CBLC) ELISA Kit
715€ (96 tests)
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Name
Human E3 Ubiquitin-Protein Ligase CBL-C (CBLC) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx386309
Tested Applications
ELISA
Description
Human E3 Ubiquitin-Protein Ligase CBL-C (CBLC) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human CBLC concentrations in tissue homogenates, cell lysates and other biological fluids.
Documentos del producto
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | E3 Ubiquitin-Protein Ligase CBL-C (CBLC) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.15 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9ULV8 |
| Gene ID | 23624 |
| OMIM | 608453 |
| Alias | CBL-C,CBLC,RNF57,CBL-SL,CBL-3 |
| Background | Elisa Kits for: CBLC |
| Status | RUO |
| Note | This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
CBLC is a member of the CBL family of ubiquitin ligases. It functions similarly to CBL and CBLB in modulating receptor signaling through ubiquitination. CBLC is involved in regulating the endocytosis and degradation of RTKs by promoting the ubiquitination of specific substrates. This regulation is essential in controlling the intensity and duration of signaling pathways that govern cell growth and differentiation. CBLC also plays a role in immune system signaling, where its activity contributes to the fine-tuning of immune cell activation. Like other CBL family members, CBLC is implicated in various diseases, including cancer and immune disorders, due to its role in regulating key cellular processes.
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