Human E3 ubiquitin-protein ligase NHLRC1 (NHLRC1) ELISA Kit

Product Graph
715€ (96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Human E3 ubiquitin-protein ligase NHLRC1 (NHLRC1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx535213
tested applications
ELISA

Description

Human E3 ubiquitin-protein ligase NHLRC1 (NHLRC1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human E3 ubiquitin-protein ligase NHLRC1 (NHLRC1) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
E3 ubiquitin-protein ligase NHLRC1 (NHLRC1)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q6VVB1
Background
Elisa kits for NHLRC1
Status
RUO
Note
Validity: The validity for this kit is 6 months.

This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Related Products

FNab05726

NHLRC1 antibody

E3 ubiquitin-protein ligase. Together with the phosphatase EPM2A/laforin, appears to be involved in the clearance of toxic polyglucosan and protein aggregates via multiple pathways. In complex with EPM2A/laforin and HSP70, suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system(UPS). Ubiquitinates the glycogen-targeting protein phosphatase subunits PPP1R3C/PTG and PPP1R3D in a laforin-dependent manner and targets them for proteasome-dependent degradation, thus decreasing glycogen accumulation. Polyubiquitinates EPM2A/laforin and ubiquitinates AGL and targets them for proteasome-dependent degradation. Also promotes proteasome-independent protein degradation through the macroautophagy pathway.

Ver Producto
abx005115

E3 Ubiquitin-Protein Ligase NHLRC1 (NHLRC1) Antibody

NHLRC1 Antibody is a Rabbit Polyclonal antibody against NHLRC1. The protein encoded by this gene is a single subunit E3 ubiquitin ligase. Laforin is polyubiquitinated by the encoded protein. Defects in this intronless gene lead to an accumulation of laforin and onset of Lafora disease, also known as progressive myoclonic epilepsy type 2 (EPM2).

Ver Producto
abx122117

E3 Ubiquitin-Protein Ligase NHLRC1 (NHLRC1) Antibody

Rabbit Polyclonal against the NHLRC1 protein.

Ver Producto