Human Folate Receptor Alpha (FOLR1) Protein

546€ (100 µg)
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name
Human Folate Receptor Alpha (FOLR1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx620335
tested applications
ELISA, WB, SDS-PAGE
Description
Human Folate Receptor Alpha (FOLR1) Protein is a recombinant Human protein produced in a Mammalian cell expression system.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Folate Receptor Alpha (FOLR1) |
Host | Mammalian cells |
Origin | Human |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 28.19 kDa Sequence Fragment: Met1-Met233 Tag: C-terminal His tag |
Expression | Recombinant |
Purity | > 90% (SDS-PAGE) |
Size 1 | 100 µg |
Size 2 | 1 mg |
Form | Liquid |
Tested Applications | ELISA, WB, SDS-PAGE |
Buffer | 0.01 M PBS, pH 7.4. |
Availability | Shipped within 5-12 working days. |
Storage | Store at 2-8 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
Dry Ice | No |
UniProt ID | P15328 |
Background | Protein FOLR1 |
Note | This product is for research use only. This product is shipped with ice packs. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.
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