Human Follistatin Like Protein 1 (FSTL1) Protein
221€ (10 µg)
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name
Human Follistatin Like Protein 1 (FSTL1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx650753
tested applications
WB, SDS-PAGE
Description
Human FSTL1 Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Follistatin Like Protein 1 (FSTL1) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Glu21-Ile308 Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 36.4 kDa |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q12841 |
| Alias | FRP,FSL1,OCC1,OCC-1,TSC36,MIR198,Follistatin-related protein 1 |
| Background | Protein FSTL1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
Follistatin like 1 (FSTL1) FSTL1 is a secreted glycoprotein that belongs to the SPARC (Secreted Protein Acidic and Rich in Cysteine)-related family and plays diverse roles in development, inflammation, and tissue repair. FSTL1 contains a follistatin-like domain that enables it to interact with various signaling molecules, including members of the TGF-β superfamily. FSTL1 modulates signaling pathways such as BMP (bone morphogenetic protein) signaling, influencing cell differentiation, growth, and immune responses. It is highly expressed in tissues undergoing development or repair, such as the heart, lungs, and skeletal muscles. FSTL1 also exhibits immunomodulatory properties, acting as a pro-inflammatory or anti-inflammatory mediator depending on the context. Dysregulation of FSTL1 has been implicated in inflammatory diseases, cardiovascular conditions, and fibrosis, where it contributes to tissue remodeling and immune dysregulation. In cancer, altered FSTL1 expression can influence tumor progression and metastasis by modulating the tumor microenvironment. Its multifunctional roles in signaling, tissue repair, and immune regulation highlight its potential as a therapeutic target.
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