Human Adhesion G-Protein Coupled Receptor G5 (ADGRG5) Protein

Este producto es parte de ADGRG - Adhesion G-protein coupled receptor G
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1118€ (100 µg)

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935106861
info@markelab.com
name
Human Adhesion G-Protein Coupled Receptor G5 (ADGRG5) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691261
tested applications
SDS-PAGE

Description

Adhesion G-Protein Coupled Receptor G5 (ADGRG5) protein is a recombinant Human protein expressed in HEK293 cells.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Adhesion G-Protein Coupled Receptor G5 (ADGRG5)
Host
HEK293 cells
Assay Type
Activity: Not tested
Sequence Fragment: Met1-Gly184
Tag: C-terminal Fc tag
Origin
Human
Observed MW
45.6 kDa
Expression
Recombinant
Purity
> 94% (SDS-PAGE)
Size 1
100 µg
Form
Lyophilized
Tested Applications
SDS-PAGE
Buffer
Prior to lyophilization: Sterile PBS, pH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Storage: Store lyophilized between -20 °C and -80°C.
Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months.
Shelf Life: 12 months.
Dry Ice
No
UniProt ID
Q8IZF4
Alias
ADGRG5,PGR27,GPR114,Gm1109,UNQ2524/PRO6017
Background
Protein ADGRG5
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Endotoxin Level: < 1.0 EU per µg (LAL method).

Descripción

Members of this family exhibit elongated N-termini and harbor multiple functional domains. They are implicated in immune system functions and central nervous system activities. Through alternative splicing, numerous transcript variants are generated, encoding diverse isoforms. ADGRG5, also known as GPR114, is expressed in immune cells such as eosinophils and has a role in modulating immune responses. It is particularly involved in allergic inflammation, contributing to immune cell adhesion and migration. ADGRG5 is under investigation for its potential role in asthma and other allergic disorders. Its specific signaling pathways are not fully elucidated, but its immune-related functions make it a promising target for therapies in allergic and inflammatory conditions.
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