Human G-Protein Coupled Receptor 56 (GPR56) Protein

Este producto es parte de ADGRG - Adhesion G-protein coupled receptor G
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1118€ (100 µg)

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935106861
info@markelab.com
name
Human G-Protein Coupled Receptor 56 (GPR56) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx692183
tested applications
SDS-PAGE

Description

Human GPR56 Protein is a recombinant protein from Human produced in HEK293 Cells. A DNA sequence encoding the human GPR56 isoform b (NP_958933.1) extracellular domain (Met 1-Val 342) was fused with a polyhistidine tag at the C-terminus.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
GPR56
Host
HEK293 cells
Assay Type
Activity: Not tested
Sequence Fragment: Met1-Val342
Tag: C-terminal His tag
Origin
Human
Observed MW
37.4 kDa
Expression
Recombinant
Purity
> 80% (SDS-PAGE)
Size 1
100 µg
Form
Lyophilized
Tested Applications
SDS-PAGE
Buffer
Lyophilized from sterile PBS, pH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Storage: Store lyophilized between -20 °C and -80°C.
Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months.
Shelf Life: 12 months.
Dry Ice
No
NCBI Accession
NP_958933.1
Alias
ADGRG1,BFPP,Cyt28,GPR56,TM7LN4,TM7XN1,BPPR,CDCBM14B,CDCBM15A
Background
Protein ADGRG1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Endotoxin Level: < 1.0 EU per µg (LAL method).

Descripción

Members of this family exhibit elongated N-termini and harbor multiple functional domains. They are implicated in immune system functions and central nervous system activities. Through alternative splicing, numerous transcript variants are generated, encoding diverse isoforms. ADGRG1, also known as GPR56, is a member of the adhesion GPCR family widely expressed in the central nervous system, immune cells, and various tissues. It plays crucial roles in brain development, particularly in cortical formation. ADGRG1 also regulates cell adhesion, migration, and tumor progression. Mutations in ADGRG1 are associated with bilateral frontoparietal polymicrogyria (BFPP), a neurological disorder. Beyond its developmental role, ADGRG1 has been implicated in cancer and immune modulation, making it a target of interest for therapeutic interventions.
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