Human Heparan Sulfate Proteoglycan 2 (HSPG2) Protein

208€ (10 µg)
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name
Human Heparan Sulfate Proteoglycan 2 (HSPG2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx067054
tested applications
WB, SDS-PAGE
Description
Human Heparan Sulfate Proteoglycan 2 (HSPG2) is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Heparan Sulfate Proteoglycan 2 (HSPG2) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Leu4149-Ser4391 Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 27.0 kDa Observed MW (SDS-PAGE): 28 kDa |
| Expression | Recombinant |
| Purity | > 97% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | P98160 |
| Alias | PLC,SJA,SJS,HSPG,SJS1, PRCAN,HSPG,Perlecan,Basement membrane-specific heparan sulfate proteoglycan core protein,Schwartz-Jampel syndrome 1,chondrodystrophic myotonia |
| Background | Protein HSPG2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
Heparan sulfate proteoglycan 2 (HSPG2), also known as perlecan, is a significant component of the extracellular matrix (ECM) in many tissues, including basement membranes. HSPG2 plays a crucial role in various physiological processes such as cell adhesion, proliferation, differentiation, and migration. It is synthesized as a large multidomain protein and is extensively glycosylated. Perlecan is ubiquitous in the body, present in vascular endothelial cells, the central nervous system, skeletal muscle, and other tissues. Its importance is underscored by its involvement in numerous developmental and pathological conditions, including cancer, cardiovascular diseases, and genetic disorders like Schwartz-Jampel syndrome and Dyssegmental Dysplasia Silverman-Handmaker type.
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