Human Interleukin 1 Receptor Type II (IL1R2) ELISA Kit
513.5€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human Interleukin 1 Receptor Type II (IL1R2) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx251184
Tested Applications
ELISA
Description
Human Interleukin 1 Receptor Type II (IL1R2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Interleukin 1 Receptor Type II concentrations in serum, plasma and other biological fluids.
Documentos del producto
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | Interleukin 1 Receptor Type II (IL1R2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 31.3 pg/ml - 2000 pg/ml |
| Sensitivity | 18.8 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | IL1R2,CD121d. IL1 RII |
| Background | Elisa Kits for: IL1R2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
IL1R2 functions as a decoy receptor for interleukin-1, competitively binding to IL-1α, IL-1β, and the IL-1 receptor accessory protein (IL1RAP) without initiating downstream signaling IL1R2 lacks an active intracellular signaling domain, thereby preventing activation of NF-κB and other pro-inflammatory pathways IL1R2 is expressed on the surface of monocytes, macrophages, and B cells, and it is also secreted in a soluble form (sIL1R2), which further neutralizes IL-1 activity in the extracellular environment By acting as a negative regulator of IL-1 signaling, IL1R2 plays an anti-inflammatory role and contributes to the resolution of immune responses IL1R2 expression is upregulated by anti-inflammatory cytokines such as IL-4 and IL-10, highlighting its role in immune regulation Dysregulation of IL1R2 is associated with inflammatory diseases, including sepsis, arthritis, and chronic autoimmune disorders, where its expression may serve as a biomarker for disease activity IL1R2’s ability to limit IL-1 activity makes it a critical target for therapeutic strategies aimed at reducing excessive inflammation and immune activation
Productos relacionados
Interleukin 1 Receptor Type II (IL1R2) Antibody
IL1R2 Antibody is a Rabbit Polyclonal antibody against IL1R2. The protein encoded by this gene is a cytokine receptor th…
Ver producto
Interleukin 1 Receptor Type II (IL1R2) Antibody
Rabbit Polyclonal against the IL1R2 protein.…
Ver producto
Human Interleukin 1 Receptor Type II (IL1R2) ELISA Kit
Human Interleukin 1 Receptor Type II (IL1R2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Huma…
Ver producto