Human Islet Amyloid Polypeptide (IAPP) Protein
403€ (20 µg)
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935106861
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name
Human Islet Amyloid Polypeptide (IAPP) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx600127
tested applications
SDS-PAGE
Description
Human Islet Amyloid Polypeptide (IAPP) Protein is a recombinant full-length protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Islet Amyloid Polypeptide (IAPP) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: 1-89 AA Tag: C-terminal His tag |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 16.7 kDa |
| Expression | Recombinant |
| Purity | > 85% (SDS-PAGE) |
| Size 1 | 20 µg |
| Size 2 | 100 µg |
| Size 3 | 1 mg |
| Tested Applications | SDS-PAGE |
| Buffer | Tris/PBS based, containing 50% glycerol. |
| Availability | Shipped within 15-25 working days. |
| Storage | Aliquot and store at -20 °C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P10997 |
| Gene ID | 3375 |
| Background | Protein IAPP |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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IAPP, also known as Amylin, is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. IAPP is co-secreted with insulin by pancreatic β-cells and largely contributes to glycemic control. Studies suggest that this protein, like the related beta-amyloid(Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes.
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