Human Junction Adhesion Molecule Like (JAML) Protein

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Description
Human JAML Protein is a recombinant protein from Human produced in HEK293 Cells. A DNA sequence encoding the human JAML (NP_001091996.1) extracellular domain (Met 1-Leu 275) was fused with a polyhistidine tag at the C-terminus.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | JAML |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Leu275 Tag: C-terminal His tag |
| Origin | Human |
| Observed MW | 30.5 kDa |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| NCBI Accession | NP_001091996.1 |
| Alias | AMICA,Gm638,AMICA1,CREA7-1,CREA7-4,Dendritic cell-specific protein,Adhesion molecule interacting with CXADR antigen 1 |
| Background | Protein JAML |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
Junctional adhesion molecule-like (JAML) protein is part of the immunoglobulin superfamily, which encompasses a wide range of proteins involved in cell-cell adhesion, immune responses, and cellular signaling. JAML is known for its critical role in the immune system, particularly in the regulation of immune cell interactions and functions. The protein is expressed predominantly on epithelial cells and various immune cells, including neutrophils and certain T-cell subsets, where it contributes to immune surveillance and tissue homeostasis.
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