Human Leucine-Rich Repeat Neuronal Protein 3 (LRRN3) Protein

Este producto es parte de LRRN - leucine rich repeat neuronal
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1118€ (100 µg)

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935106861
info@markelab.com
name
Human Leucine-Rich Repeat Neuronal Protein 3 (LRRN3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691438
tested applications
SDS-PAGE

Description

Human LRRN3 Protein is a recombinant protein from Human produced in Baculovirus-Insect Cells. A DNA sequence encoding the human LRRN3 (AAH35133.1) extracellular domain (Met 1-Thr 628) was fused with a polyhistidine tag at the C-terminus.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
LRRN3
Host
Insect
Assay Type
Activity: Not tested
Sequence Fragment: Met1-Thr628
Tag: C-terminal His tag
Origin
Human
Observed MW
70 kDa
Expression
Recombinant
Purity
> 90% (SDS-PAGE)
Size 1
100 µg
Form
Lyophilized
Tested Applications
SDS-PAGE
Buffer
Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.0, 10% gly.
Availability
Shipped within 5-15 working days.
Storage
Storage: Store lyophilized between -20 °C and -80°C.
Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months.
Shelf Life: 12 months.
Dry Ice
No
NCBI Accession
AAH35133.1
Alias
NLRR3,NLRR-3,FIGLER5, Neuronal leucine-rich repeat protein 3
Background
Protein LRRN3
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Endotoxin Level: < 1.0 EU per µg (LAL method).

Descripción

LRRN3 is another member of the LRR neuronal protein family and is predominantly expressed in the central nervous system. It plays a significant role in neural connectivity and synaptic modulation, contributing to the development of functional neural networks. LRRN3’s expression is tightly regulated during embryonic brain development, particularly in areas associated with sensory processing and motor control. This protein facilitates cell signaling and neural migration through its leucine-rich repeat domains, which promote specific interactions with other synaptic and extracellular proteins. LRRN3 is being studied for its potential involvement in neuropsychiatric conditions such as autism spectrum disorders (ASD) and schizophrenia, where synaptic and connectivity abnormalities are prevalent. Understanding LRRN3’s function could provide insights into therapeutic targets for these conditions.
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