Human Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3) Protein

234€ (10 µg)
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935106861
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name
Human Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx067777
tested applications
WB, SDS-PAGE
Description
Human Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3) is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Val219-Gly438 Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 27.0 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8N6C8 |
| Alias | Leukocyte immunoglobulin-like receptor subfamily A member 3,HM31,HM43,ILT6,LIR4,CD85E,ILT-6,LIR-4,Immunoglobulin-like transcript 6,Leukocyte immunoglobulin-like receptor 4,Monocyte inhibitory receptor HM43/HM31 |
| Background | Protein LILRA3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
LILRA3 (Leukocyte Immunoglobulin-Like Receptor A3), also referred to as ILT6 or CD85e, is an intriguing member of the leukocyte immunoglobulin-like receptor (LILR) family, which is predominantly expressed on immune cells. LILRA3 is unique among LILR family members because it lacks a transmembrane domain, functioning as a soluble molecule. Found within the Leukocyte Receptor Complex (LRC) on chromosome 19q13.4, LILRA3 plays a significant role in modulating immune responses, particularly in inflammatory pathways. As a soluble receptor, LILRA3 is capable of binding various ligands, which include MHC class I molecules, and thus can modulate signaling pathways related to immune tolerance and immune response activation. Its specific function in the immune system remains somewhat enigmatic, as both pro-inflammatory and inhibitory effects have been suggested. However, it is recognized as a key player in regulating inflammation and immune homeostasis, with particular relevance in autoimmune diseases, infections, and certain cancers
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