Human Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 2 (LILRB2) Protein

221€ (10 µg)
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935106861
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name
Human Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 2 (LILRB2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168118
tested applications
WB, SDS-PAGE
Description
Human Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 2 Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 2 (LILRB2) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Leu53-Val255 Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 26.4 kDa Observed MW (SDS-PAGE): 26 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8N423 |
| Alias | Leukocyte immunoglobulin-like receptor subfamily B member 2,Leukocyte immunoglobulin-like receptor 2,ILT4,LIR2,CD85D,ILT-4,LIR-2,MIR10,MIR-10,CD85 antigen-like family member D,Immunoglobulin-like transcript 4,Monocyte/macrophage immunoglobulin-like receptor 10 |
| Background | Protein LILRB2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
LILRB2, also known as Leukocyte Immunoglobulin-Like Receptor Subfamily B Member 2, ILT4 (Immunoglobulin-Like Transcript 4), or CD85d, is an inhibitory receptor expressed on immune cells, especially on myeloid cells, such as monocytes, macrophages, dendritic cells, and some granulocytes. It is part of the LILR family (leukocyte immunoglobulin-like receptors), which is encoded within the LRC (Leukocyte Receptor Complex) on chromosome 19q13.4. LILRB2 plays a major role in immune homeostasis by binding to MHC class I molecules and other ligands, leading to suppression of immune responses. This makes it a central player in controlling inflammation, self-tolerance, and response to chronic infections and tumors.
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