Human Lymphocyte antigen 75 (LY75) ELISA Kit

715€ (96 tests)
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935106861
info@markelab.com
name
Human Lymphocyte antigen 75 (LY75) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx531769
tested applications
ELISA
Description
Human Lymphocyte antigen 75 (LY75) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Lymphocyte antigen 75 (LY75) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Lymphocyte antigen 75 (LY75) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O60449 |
| OMIM | 604524 |
| Alias | C-type lectin domain family 13 member B,CD205,LY-75,CLEC13B,DEC-205,GP200-MR6,Lymphocyte antigen 75 |
| Background | Elisa Kits for: LY75 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
LY75, also known as lymphocyte antigen 75, is a protein primarily involved in the immune system, specifically in antigen processing and presentation. LY75 is also referred to as DEC-205 (dendritic and epithelial cell 205) and is encoded by the LY75 gene in humans. LY75 belongs to the C-type lectin receptor family, which includes proteins involved in recognizing carbohydrate structures on pathogens, facilitating immune cell recognition, and initiating immune responses. It is a type I transmembrane protein highly expressed in dendritic cells (DCs), especially in lymphoid tissues, and also found on certain types of epithelial cells. Through its antigen-capturing ability, LY75 has a significant role in promoting immune tolerance and in the activation of T cells. LY75 functions as a receptor that binds to specific antigens, internalizes them, and processes them for presentation on major histocompatibility complex (MHC) molecules, primarily MHC class II. This makes it a critical component in activating adaptive immune responses, especially against infections, tumors, and other immune challenges. The ability of LY75 to capture and process antigens, combined with its expression pattern, positions it as an important target for immunotherapy, especially in contexts where modulation of the immune response, such as cancer immunotherapy and vaccine development, is desired.
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