Human Microfibrillar-associated protein 2 (MFAP2) ELISA Kit

715€ (96 tests)
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935106861
info@markelab.com
name
Human Microfibrillar-associated protein 2 (MFAP2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx532842
tested applications
ELISA
Description
Microfibrillar-Associated Protein 2 (MFAP2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Microfibrillar-Associated Protein 2 (MFAP2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Microfibrillar-Associated Protein 2 (MFAP2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.06 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P55001 |
| Gene ID | 4237 |
| OMIM | 156790 |
| Alias | MAGP,MAGP1,MAGP-1,MFAP-2 |
| Background | Elisa Kits for: MFAP2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
Microfibril Associated Protein 2 (MFAP2), also known as MAGP-1, is a component of the extracellular matrix associated with microfibrils. MFAP2 interacts with fibrillin and elastin to contribute to the structural integrity and elastic properties of connective tissues. It plays a role in modulating signaling pathways such as TGF-β and BMP, which are crucial for tissue homeostasis, repair, and development. Dysregulation of MFAP2 has been implicated in connective tissue disorders, including Marfan syndrome and aortic aneurysms, due to its impact on microfibril assembly and extracellular matrix stability. MFAP2 also has emerging roles in angiogenesis and tumor progression, where it influences the extracellular microenvironment and cell signaling.
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