Human Myosin VIIB (MYO7B) Protein
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Description
Human Myosin VIIB (MYO7B) Protein is a recombinant Human protein expressed in E. coli.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Myosin VIIB (MYO7B) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Please enquire. Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| Alias | Unconventional myosin-VIIb |
| Background | Protein MYO7B |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Descripción
Myosin VIIB (MYO7B) is a motor protein from the myosin family, which is involved in ATP-dependent cellular movements Myosin VIIB, like other myosins, moves along actin filaments, converting chemical energy into mechanical work This motor protein is crucial for cellular processes such as vesicular transport, endocytosis, and cell migration MYO7B plays a specific role in the auditory and visual systems, where it is involved in the function of sensory cells, including the hair cells of the inner ear and photoreceptors in the retina In the inner ear, MYO7B helps maintain the structure and function of hair cells, which are responsible for detecting sound vibrations and balancing signals Disruption in MYO7B function leads to hearing loss and progressive blindness, as seen in Usher syndrome type 2, where both deafness and vision impairment occur due to defects in inner ear and retinal cells
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