Human Nucleoporin 188 kDa (NUP188) ELISA Kit

Este producto es parte de NUP - nucleoporin
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715€ (96 tests)

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935106861
info@markelab.com
name
Human Nucleoporin 188 kDa (NUP188) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx354442
tested applications
ELISA

Description

Human Nucleoporin 188 kDa (NUP188) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Nucleoporin 188 kDa (NUP188) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
ELISA Kits
Immunogen Target
Nucleoporin 188 kDa (NUP188)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.312 ng/ml - 20 ng/ml
Sensitivity
< 0.12 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q5SRE5
Alias
hNup188,KIAA0169,SANDSTEF,Nucleoporin NUP188
Background
Elisa Kits for: NUP188
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Descripción

Nucleoporin 188 (NUP188) is an essential component of the nuclear pore complex (NPC), which regulates the selective transport of molecules between the nucleus and cytoplasm NUP188 participates in the structure and function of the nuclear pore, interacting with other nucleoporins to form the central channel that facilitates the movement of RNA, proteins, and other macromolecules across the nuclear envelope NUP188 plays a significant role in ensuring the proper nuclear-cytoplasmic exchange, which is critical for maintaining cellular processes such as gene expression, signal transduction, and cell cycle regulation Additionally, NUP188 is involved in the assembly and stability of the nuclear pore complex and may influence cell division and the response to DNA damage and oxidative stress Dysregulation of NUP188 has been associated with several diseases, including cancers, where defects in nucleocytoplasmic transport lead to uncontrolled cell growth and poor prognosis NUP188’s role in maintaining nuclear structure and regulating transport underscores its importance in cellular integrity and function

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