Human Receptor-Type Tyrosine-Protein Phosphatase F (PTPRF) Protein

Este producto es parte de PTPR - protein tyrosine phosphatase receptor type
Product Graph
221€ (10 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Human Receptor-Type Tyrosine-Protein Phosphatase F (PTPRF) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168855
tested applications
WB, SDS-PAGE

Description

Human PTPRF Protein is a recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Receptor-Type Tyrosine-Protein Phosphatase F (PTPRF)
Host
E. coli
Assay Type
Activity: Not tested
Sequence Fragment: Asp30-Tyr224
Tag: N-terminal His tag
Origin
Human
Conjugation
Unconjugated
Observed MW
Calculated MW: 24.8 kDa  Observed MW (SDS-PAGE): 27 kDa
Expression
Recombinant
Purity
> 97%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles.
Dry Ice
No
UniProt ID
P10586
Alias
LAR,BNAH2,Leukocyte common antigen related,Receptor-type tyrosine-protein phosphatase F
Background
Protein PTPRF
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Concentration: Prior to lyophilization: 200 µg/ml

Descripción

PTPRF, also known as leukocyte common antigen-related (LAR) protein, is a receptor-like protein tyrosine phosphatase involved in cell-cell adhesion, neuronal development, and tissue organization. Structurally, PTPRF contains extracellular immunoglobulin-like (Ig) domains, fibronectin type III domains, a single transmembrane region, and two intracellular phosphatase domains, where the first exhibits enzymatic activity. PTPRF plays a critical role in synaptic formation, axonal guidance, and neuronal differentiation through interactions with ligands like netrin-G ligands and heparan sulfate proteoglycans. It regulates focal adhesion and cytoskeletal organization by interacting with intracellular proteins such as liprin-α. Mutations or dysregulation of PTPRF have been implicated in cancers, insulin resistance, and neurological disorders, including intellectual disability and autism.

Related Products

EH2492

Human PTPRF (Receptor-type tyrosine-protein phosphatase F) ELISA Kit

Ver Producto
FNab10951

PTPRF antibody

Ver Producto
abx006780

Receptor-Type Tyrosine-Protein Phosphatase F (PTPRF) Antibody

PTPRF Antibody is a Rabbit Polyclonal Antibody against PTPRF.

Ver Producto