Human TLR8 (Toll-like receptor 8) ELISA Kit
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human TLR8 (Toll-like receptor 8) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH4931
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.156-10ng/ml |
| Sensitivity | 0.094ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | Q9NR97 |
| Alias | Toll-like receptor 8,CD288,IMD98,TLR-8,hTLR8 |
| Background | Elisa kits for TLR8 |
| Status | RUO |
Background
Toll-like receptor 8 (TLR8) is a member of the toll-like receptor family, which plays a crucial role in the innate immune system by recognizing specific molecular patterns associated with pathogens. TLR8, in particular, is an endosomal receptor that primarily recognizes single-stranded RNA (ssRNA) from viruses and other microorganisms, making it a significant player in detecting RNA viruses, such as influenza and certain coronaviruses. As part of the pattern recognition receptor (PRR) family, TLR8 is instrumental in initiating the innate immune response upon detection of foreign RNA, leading to the production of inflammatory cytokines and antiviral responses. TLR8 expression is largely found within immune cells, specifically in monocytes, macrophages, and dendritic cells, with notable expression in myeloid dendritic cells. Its activation is associated with the MyD88-dependent signaling pathway, which ultimately results in the production of cytokines and type I interferons (IFNs), essential mediators in controlling viral infections. TLR8’s unique role in recognizing RNA-based pathogens positions it as a potential therapeutic target for treating viral infections, certain inflammatory diseases, and possibly cancers.
Productos relacionados
Toll Like Receptor 8 (TLR8) Antibody
TLR8 Antibody is a Rabbit Polyclonal antibody against TLR8. The Toll-like Receptors (TLR) are a family of human receptor…
Ver producto
Toll Like Receptor 8 (TLR8) Antibody
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pa…
Ver producto
Mouse TLR8 Antibody
TLR8 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activ…
Ver producto