Human Tumor Necrosis Factor Ligand Superfamily Member 4 (TNFSF4) Protein

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Description
Human Tumor Necrosis Factor Ligand Superfamily Member 4 (TNFSF4) Protein is a recombinant Human protein produced in a Mammalian cell expression system.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Tumor Necrosis Factor Ligand Superfamily Member 4 (TNFSF4) |
| Host | Mammalian cells |
| Assay Type | Activity: Not tested Sequence Fragment: Gln51-Leu183 Tag: C-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 18.70 kDa |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20 °C to 80°C. Avoid repeated freeze-thaw cycles. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | P23510 |
| Alias | Tumor necrosis factor ligand superfamily member 4,GP34,CD252,OX4OL,TXGP1,CD134L,OX-40L,TNLG2B,OX40 ligand,OX40L,TAX transcriptionally-activated glycoprotein 1 |
| Background | Protein TNFSF4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in sterile water to produce a stock solution. |
Descripción
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The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig and CD40-stimulated B cells, this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells.
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