Human YWHAB (14-3-3 protein Beta/Alpha) ELISA Kit
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human YWHAB (14-3-3 protein Beta/Alpha) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH4008
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 3.125-200ng/ml |
| Sensitivity | 1.875ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | P31946 |
| Alias | YWHAB, GW128, HEL-S-1, HS1, KCIP-1, YWHAA, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta,14-3-3 alpha,14-3-3 beta |
| Background | Elisa kits for YWHAB |
| Status | RUO |
Background
YWHAB, part of the 14-3-3 protein family, functions as a scaffold protein that binds to phosphorylated serine/threonine-containing motifs, regulating protein localization, stability, and signaling pathways. It is involved in processes such as cell cycle control, DNA damage response, apoptosis, and stress adaptation by interacting with key signaling proteins, including Raf kinases, BAD, and CDC25. YWHAB regulates pathways like MAPK and PI3K/Akt, influencing cellular growth, survival, and metabolism. It is ubiquitously expressed, with high levels in the brain, where it contributes to synaptic plasticity, neuroprotection, and neuronal development. Dysregulation of YWHAB has been associated with neurodegenerative diseases, including Alzheimer’s and Parkinson’s, as well as cancer, where altered protein interactions promote tumor survival and metastasis. Knockout studies show defects in cellular proliferation, increased apoptosis, and impaired stress responses, highlighting its role in maintaining cellular stability and signaling balance.
Productos relacionados
14-3-3 Protein Beta/Alpha (YWHAB) Antibody
YWHAB Antibody is a Rabbit Polyclonal antibody against YWHAB. This gene encodes a protein belonging to the 14-3-3 family…
Ver producto
14-3-3 Beta (YWHAB) Antibody
Rabbit polyclonal antibody against 14-3-3 beta protein. Immunogen region is Internal.…
Ver producto
14-3-3 Beta/alpha (YWHAB) Antibody
14-3-3 beta/alpha Antibody is a Mouse Monoclonal antibody against Human, Mouse and Rat.…
Ver producto