Importin Subunit Alpha-2 (KPNA2) Peptide
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Importin Subunit Alpha-2 (KPNA2) Peptide is a synthetic peptide. This peptide is used in the production of
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Importin Subunit Alpha-2 (KPNA2) |
| Host | Synthetic |
| Assay Type | Activity: Not tested. Sequence Fragment: C-Terminus: C-QVQDGAPGTFNF |
| Recommended Dilution | BL (predicted): 0.5 mg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | P-ELISA |
| Buffer | Prior to lyophilization: Deionized water. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 3838, 16647, 85245 |
| NCBI Accession | NP_002257.1 |
| Alias | KPNA2,IPOA1, QIP2, RCH1, SRP1alpha, Karyopherin alpha 2, SRP1-alpha, karyopherin subunit alpha 2, PTAC58 |
| Background | Protein KPNA2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in deionized water. |
Descripción
Related Products
Human KPNA2 (Importin subunit alpha-2) ELISA Kit
Ver Producto
KPNA2 antibody
Functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Docking of the importin/substrate complex to the nuclear pore complex(NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and-beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus.
Ver Producto