Inosine Triphosphate Pyrophosphatase (ITPA) Antibody

312€ (60 µl)
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935106861
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name
Inosine Triphosphate Pyrophosphatase (ITPA) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx001133
tested applications
WB
Description
ITPA Antibody is a Rabbit Polyclonal antibody against ITPA. ITPA(Inosine triphosphate pyrophosphatase) catalyzes the pyrophosphohydrolysis of inosine triphosphate (ITP) to inosine monophosphate (IMP).It expresses in the cytoplasm(PMID:11278832).It can be detected a band of 44 Kda as a homodimer in the western blot(PMID:19631656) though its predictedsize is 21kd.This protein has two isforms with the molecular weight of 20KDa and 21KDa.This antibody is specific to this protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Inosine Triphosphate Pyrophosphatase (ITPA) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by affinity chromatography. |
Size 1 | 60 µl |
Size 2 | 120 µl |
Size 3 | 200 µl |
Form | Liquid |
Tested Applications | WB |
Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q9BY32 |
Gene ID | 3704 |
NCBI Accession | NP_258412.1 |
Background | Antibody anti-ITPA |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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ITPA antibody
Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate(ITP), deoxyinosine triphosphate(dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate(dHAPTP) and xanthosine 5'-triphosphate(XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy-and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
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