Insulin Gene Enhancer Protein ISL-1 (ISL1) Antibody
383.5€ (100 µl)
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935106861
info@markelab.com
name
Insulin Gene Enhancer Protein ISL-1 (ISL1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx011019
tested applications
ELISA, IHC, IF/ICC
Description
ISL1 (ISL1 transcription factor, LIM/homeodomain) is a member of the LIM/homeodomain family of transcription factors. It binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. It is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Mutations in this gene have been associated with maturity-onset diabetes of the young.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Insulin Gene Enhancer Protein ISL-1 (ISL1) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Unpurified ascites. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IF/ICC |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P61371 |
| Gene ID | 3670 |
| OMIM | 600366 |
| Background | Antibody anti-ISL1 |
| Status | RUO |
| Note | Concentration: Not determined. - |
Descripción
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Insulin Gene Enhancer Protein ISL-1 (ISL1) Antibody
ISL1 Antibody is a Rabbit Polyclonal antibody against ISL1. This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.
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