Integrin Alpha 4 (ITGA4) Antibody
1274€ (1 ml)
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935106861
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name
Integrin Alpha 4 (ITGA4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx170122
tested applications
FCM
Description
Integrin Alpha 4 (ITGA4) Antibody is a recombinant Mouse Monoclonal against ITGA4.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Integrin Alpha 4 (ITGA4) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB (Predicted): 0.2-2 µg/ml, IHC (Predicted): 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml, FCM: 10 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2b Kappa |
| Expression | Recombinant |
| Purification | Purified by affinity chromatography. |
| Size 1 | 1 ml |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P13612 |
| Background | Antibody anti-ITGA4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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ITGA4, also named as CD49D, belongs to the integrin alpha chain family. ITGA4 is a receptor for fibronectin, VCAM1 and MADCAM1. ITGA4 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. It recognizes the sequence Q-I-D-S in VCAM1. I It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells ITGA4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
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