Interferon Alpha/Beta Receptor 2 (IFNAR2) Antibody

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169€ (20 µl)

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935106861
info@markelab.com
name
Interferon Alpha/Beta Receptor 2 (IFNAR2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx320076
tested applications
ELISA, IHC

Description

IFNAR2 Antibody is a Rabbit Polyclonal against IFNAR2.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Interferon Alpha/Beta Receptor 2 (IFNAR2)
Immunogen: Recombinant human Interferon alpha/beta receptor 2 protein (27-243AA).
Host
Rabbit
Reactivity
Human
Recommended Dilution
IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Antigen Affinity Chromatography.
Size 1
20 µl
Size 2
50 µl
Size 3
100 µl
Size 4
200 µl
Size 5
1 ml
Form
Liquid
Tested Applications
ELISA, IHC
Buffer
PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P48551
Gene ID
3455
NCBI Accession
NP_000865.2, NM_000874.4, NP_001276054.1, NM_001289125.1
OMIM
602376
Background
Antibody anti-IFNAR2
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

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Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation(PubMed:26424569). Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1(PubMed:8181059, PubMed:7665574, PubMed:7759950). Isoform 3 is a potent inhibitor of type I IFN receptor activity(PubMed:7759950).

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