Interleukin 15 (IL-15) Antibody

Este producto es parte de IL15 - interleukin 15
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442€ (200 µl)

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935106861
info@markelab.com
name
Interleukin 15 (IL-15) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx432855
tested applications
P-ELISA, WB

Description

IL-15 Antibody is a Goat Polyclonal antibody against IL-15.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Interleukin 15 (IL-15)
Immunogen: abx616916 - Internal region, 70-82 AA: C-DATLYTESDVHPS
Host
Goat
Reactivity
Human
Assay Type
Concentration: 0.5 mg/ml
Recommended Dilution
P-ELISA: 1/128000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Size 1
200 µl
Form
Liquid
Tested Applications
P-ELISA, WB
Buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Gene ID
3600
NCBI Accession
NP_000576.1, NP_751915.1
Alias
IL-15
Background
Antibody anti-IL15
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

Interleukin 15 (IL15) is a pro-inflammatory cytokine that plays a crucial role in regulating innate and adaptive immune responses, particularly by supporting the development, activation, and survival of natural killer (NK) cells and CD8+ T cells. IL-15 is essential for immune surveillance and protection against viral infections and tumors, making it an important cytokine in both immunity and immunotherapy. IL-15 was first identified as a T-cell growth factor similar to IL-2, but it is now recognized as a distinct cytokine with a unique biological role. It is expressed by a wide range of cell types, including monocytes, macrophages, dendritic cells, epithelial cells, and fibroblasts, in response to various inflammatory stimuli. Unlike many cytokines that are secreted and act in an autocrine or paracrine fashion, IL-15 primarily functions through a unique mechanism called trans-presentation, where it binds to its receptor on neighboring cells via cell-cell contact, thus delivering potent activation signals.

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