Interleukin 21 (IL21) Antibody

Este producto es parte de IL21 - interleukin 21
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169€ (20 µl)

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935106861
info@markelab.com
name
Interleukin 21 (IL21) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx320186
tested applications
ELISA, IHC

Description

IL21 Antibody is a Rabbit Polyclonal against IL21.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Interleukin 21 (IL21)
Immunogen: Recombinant human Interleukin-21 protein (25-162AA).
Host
Rabbit
Reactivity
Human
Assay Type
Concentration: 0.25 mg/ml
Recommended Dilution
IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Antigen Affinity Chromatography.
Size 1
20 µl
Size 2
50 µl
Size 3
100 µl
Size 4
200 µl
Size 5
1 ml
Form
Liquid
Tested Applications
ELISA, IHC
Buffer
PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9HBE4
Gene ID
59067
NCBI Accession
NP_001193935.1
OMIM
605384
Alias
Za11,IL-21,CVID11
Background
Antibody anti-IL21
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

Interleukin 21 (IL21) is a potent cytokine produced primarily by activated CD4+ T cells, particularly T follicular helper (Tfh) cells and T helper 17 (Th17) cells. It belongs to the type I cytokine family and plays a critical role in regulating both innate and adaptive immune responses. IL-21 acts on a variety of immune cells, including B cells, T cells, natural killer (NK) cells, and dendritic cells (DCs), modulating their proliferation, differentiation, and functional activities. Its broad immunomodulatory effects make it a key regulator of immune homeostasis, inflammation, and host defense against pathogens and tumors. IL-21 is crucial for the development of germinal centers and the production of high-affinity antibodies, particularly through its regulation of B cell differentiation and antibody class switching. It also plays a significant role in promoting the cytotoxic activity of NK cells and CD8+ T cells, which are essential for anti-tumor and antiviral immunity

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