Interleukin 21 (IL21) Antibody
377€ (100 µg)
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935106861
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name
Interleukin 21 (IL21) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx234251
tested applications
ELISA, WB, IHC
Description
IL21 Antibody is a Rabbit Polyclonal against IL21.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Interleukin 21 (IL21) Immunogen: interleukin 21 |
| Host | Rabbit |
| Reactivity | Mouse, Rat |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 18 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9HBE4 |
| Alias | Za11,IL-21,CVID11 |
| Background | Antibody anti-IL21 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Interleukin 21 (IL21) is a potent cytokine produced primarily by activated CD4+ T cells, particularly T follicular helper (Tfh) cells and T helper 17 (Th17) cells. It belongs to the type I cytokine family and plays a critical role in regulating both innate and adaptive immune responses. IL-21 acts on a variety of immune cells, including B cells, T cells, natural killer (NK) cells, and dendritic cells (DCs), modulating their proliferation, differentiation, and functional activities. Its broad immunomodulatory effects make it a key regulator of immune homeostasis, inflammation, and host defense against pathogens and tumors. IL-21 is crucial for the development of germinal centers and the production of high-affinity antibodies, particularly through its regulation of B cell differentiation and antibody class switching. It also plays a significant role in promoting the cytotoxic activity of NK cells and CD8+ T cells, which are essential for anti-tumor and antiviral immunity
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