Interleukin 31 (IL31) Antibody
299€ (100 µl)
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935106861
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name
Interleukin 31 (IL31) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx132119
tested applications
WB
Description
Interleukin 31 Antibody is a Mouse Monoclonal against Interleukin 31.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Interleukin 31 (IL31) Immunogen: Cys55-Glu183+CRLDSSTTTTTTTTN |
| Host | Mouse |
| Reactivity | Rat |
| Recommended Dilution | WB: 0.01-5 µg/ml, IHC (Predicted): 5-30 µg/ml, IF/ICC (Predicted): 5-30 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2b Kappa |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | D3ZIP0 |
| Alias | IL-31 |
| Background | Antibody anti-IL31 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Interleukin 31 (IL31) is a cytokine belonging to the IL-6 cytokine family that plays a central role in the regulation of immune responses and is heavily implicated in inflammatory processes, particularly in chronic pruritic (itching) skin disorders. IL-31 is primarily produced by activated T helper 2 (Th2) cells, a subset of T cells involved in allergic responses and the regulation of immune responses to extracellular pathogens. IL-31 was discovered as a cytokine that can link the immune system with the nervous system, particularly in the skin, where it triggers pruritus and inflammatory responses. The IL-31 receptor is widely expressed, being found on keratinocytes, fibroblasts, epithelial cells, and immune cells, which suggests its involvement in skin and tissue homeostasis
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