Keratin, Type I Cytoskeletal 18 (KRT18) Antibody (Biotin)
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Description
Cytokeratin 18 Antibody is a Mouse Monoclonal against Cytokeratin 18 for use with mammalian samples.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Keratin, Type I Cytoskeletal 18 (KRT18) |
| Host | Mouse |
| Reactivity | General |
| Recommended Dilution | WB: 1-2 μg/ml, FCM: 1-4 μg/ml. Validated in IHC-P. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Biotin |
| Isotype | IgG1 |
| Clone ID | H265 |
| Size 1 | 0.1 mg |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM, IP |
| Buffer | PBS solution with 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8°C. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P05783 |
| Gene ID | 3875 |
| Background | Antibody anti-KRT18 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT18, also named as CYK18, PIG46 and K18, is the most commonly found members of the intermediate filament gene family. KRT18 is a type I keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas.
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