Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antibody

Este producto es parte de HAVCR1 - hepatitis A virus cellular receptor 1
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286€ (100 µl)

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935106861
info@markelab.com
name
Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx173255
tested applications
IHC

Description

Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antibody is a Mouse Monoclonal antibody against Hepatitis A Virus Cellular Receptor 1 (HAVCR1).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Hepatitis A Virus Cellular Receptor 1 (HAVCR1)
Immunogen: abx067645 - Recombinant Rat HAVCR1 (Tyr22-Gly235) expressed in E. coli
Host
Mouse
Reactivity
Rat
Recommended Dilution
WB (Predicted): 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG1 Kappa
Purification
Purified by Protein A and Protein G affinity chromatography.
Size 1
100 µl
Size 2
200 µl
Size 3
1 ml
Form
Liquid
Tested Applications
IHC
Buffer
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Availability
Shipped within 5-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
O54947
Gene ID
286934
Alias
Kidney injury molecule 1,TIM,KIM1,TIM1,CD365,HAVCR,KIM-1,TIM-1,TIMD1,TIMD-1,HAVCR-1,T-cell immunoglobulin and mucin domain-containing protein 1,T-cell immunoglobulin mucin receptor 1,T-cell membrane protein 1
Background
Antibody anti-HAVCR1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

Hepatitis A Virus Cellular Receptor 1 (HAVCR1), also known as TIM-1 (T-cell immunoglobulin and mucin domain-containing protein 1), is a receptor protein expressed primarily on the surface of kidney epithelial cells and various immune cells. It is a member of the TIM family of proteins, which includes other receptors like TIM-3 and TIM-4. HAVCR1 plays a critical role in immune regulation, cell signaling, and disease pathogenesis, particularly within inflammatory and immune-mediated conditions. Initially identified as the receptor for hepatitis A virus (HAV), HAVCR1 has since been associated with numerous physiological and pathological processes, including immune cell activation, tissue inflammation, and the regulation of T-cell responses. HAVCR1 is implicated in immune tolerance and modulation of immune responses, making it relevant in autoimmune disorders, infections, and cancer.

Related Products

abx067645

Rat Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Protein

Rat Hepatitis A Virus Cellular Receptor 1 (HAVCR1) protein is a recombinant protein expressed in E. coli.

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