Killer Cell Immunoglobulin Like Receptor 3DL3 (KIR3DL3) Antibody
286€ (100 µl)
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935106861
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name
Killer Cell Immunoglobulin Like Receptor 3DL3 (KIR3DL3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx104485
tested applications
WB, IHC, IF/ICC
Description
Polyclonal Antibody to Killer Cell Immunoglobulin Like Receptor 3DL3 (KIR3DL3).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Killer Cell Immunoglobulin Like Receptor 3DL3 (KIR3DL3) Immunogen: abx067654 - Recombinant KIR3DL3 (Asp147-Val410 with N-terminal His and GST tags) expressed in E. coli |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8N743 |
| Alias | KIR44,KIRC1,CD158Z,KIR3DL7,KIR2DL5B,CD158 antigen-like family member Z,Killer cell inhibitory receptor 1 |
| Background | Antibody anti-KIR3DL3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Killer Cell Immunoglobulin-Like Receptor 3DL3 (KIR3DL3), another member of the KIR family, is expressed primarily on NK cells and a subset of T cells, contributing to the modulation of innate and adaptive immune responses. While less well-characterized than other KIR family members, KIR3DL3 is thought to provide inhibitory signals upon binding to its ligands, which include specific HLA class I molecules. Its expression and function are tightly regulated, and genetic studies suggest a role in immune system variability, with potential implications in transplantation immunology and disease susceptibility. Emerging research is exploring the relevance of KIR3DL3 in the context of immune evasion by tumors and infectious agents, emphasizing its potential as a target for enhancing immune responses in therapeutic settings.
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Human Killer Cell Immunoglobulin Like Receptor 3DL3 (KIR3DL3) Protein
Human Killer Cell Immunoglobulin Like Receptor 3DL3 (KIR3DL3) is a recombinant Human protein expressed in E. coli.
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