Long-Chain-Fatty-Acid--CoA Ligase 5 (ACSL5) Antibody
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Description
Long-Chain-Fatty-Acid--CoA Ligase 5 (ACSL5) Antibody is a Rabbit polyclonal antibody for the detection of Human Long-Chain-Fatty-Acid--CoA Ligase 5 (ACSL5).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Long-Chain-Fatty-Acid--CoA Ligase 5 (ACSL5) Immunogen: Recombinant Long-Chain-Fatty-Acid--CoA Ligase 5 (Arg432-Asp683) expressed in E. coli. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9ULC5 |
| Gene ID | 51703 |
| NCBI Accession | NP_057318.2 |
| Alias | ACS2,ACS5,DIAR13,FACL5 |
| Background | Antibody anti-ACSL5 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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Acyl-CoA synthetases(ACSL) activate long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL5 may activate fatty acids from exogenous sources for the synthesis of triacylglycerol destined for intracellular storage(By similarity). Utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids(By similarity). It was suggested that it may also stimulate fatty acid oxidation(By similarity). At the villus tip of the crypt-villus axis of the small intestine may sensitize epithelial cells to apoptosis specifically triggered by the death ligand TRAIL. May have a role in the survival of glioma cells.
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