Matrix Metalloproteinase-16 (MMP16) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Matrix Metalloproteinase-16 (MMP16) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P51512 |
| Background | Antibody anti-MMP16 |
| Status | RUO |
Descripción
Related Products
Matrix Metalloproteinase-16 (MMP16) Antibody
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene for MMP16 produces two transcripts, which encode a membrane-bound form and a soluble form of the protein. Both forms of the protein activate MMP2 by cleavage. This gene was once referred to as MT-MMP2, but was renamed as MT-MMP3 or MMP16.
Ver Producto
Matrix Metalloproteinase-16 (MMP16) Antibody
Rabbit Polyclonal against the MMP16 protein.
Ver Producto
Human Matrix Metalloproteinase 16 (MMP16) ELISA Kit
Human Matrix Metalloproteinase 16 (MMP16) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human MMP16 concentrations in serum, plasma, tissue homogenates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of MMP16
Ver Producto