Microfibrillar Associated Protein 2 (MFAP2) Antibody

Este producto es parte de MFAP - microfibril associated protein
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299€ (100 µl)

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935106861
info@markelab.com
name
Microfibrillar Associated Protein 2 (MFAP2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx130304
tested applications
IHC

Description

Microfibrillar Associated Protein 2 Antibody is a Rabbit Polyclonal against Microfibrillar Associated Protein 2.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Target: Microfibrillar Associated Protein 2 (MFAP2)
Immunogen: abx167931 - Recombinant Rat MFAP2 Protein (Leu8-Cys171), expressed in E. coli.
Host
Rabbit
Reactivity
Rat
Assay Type
Concentration: 1 mg/ml
Recommended Dilution
WB (Predicted): 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Size 1
100 µl
Size 2
200 µl
Size 3
1 ml
Form
Liquid
Tested Applications
IHC
Buffer
PBS, pH 7.4, containing 0.02% sodium azide, 50% glycerol.
Availability
Shipped within 5-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
MAGP,MAGP1,MAGP-1,MFAP-2
Background
Antibody anti-MFAP2
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

Microfibril Associated Protein 2 (MFAP2), also known as MAGP-1, is a component of the extracellular matrix associated with microfibrils. MFAP2 interacts with fibrillin and elastin to contribute to the structural integrity and elastic properties of connective tissues. It plays a role in modulating signaling pathways such as TGF-β and BMP, which are crucial for tissue homeostasis, repair, and development. Dysregulation of MFAP2 has been implicated in connective tissue disorders, including Marfan syndrome and aortic aneurysms, due to its impact on microfibril assembly and extracellular matrix stability. MFAP2 also has emerging roles in angiogenesis and tumor progression, where it influences the extracellular microenvironment and cell signaling.

Related Products

abx167931

Rat Microfibrillar Associated Protein 2 (MFAP2) Protein

Rat Microfibrillar Associated Protein 2 is a recombinant Rat protein expressed in E. coli.

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