Mouse Activin A Receptor Type 2B (ACVR2B) Protein (Active)

Este producto es parte de ACVR - Activin A Receptor Type
Product Graph
1118€ (100 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Mouse Activin A Receptor Type 2B (ACVR2B) Protein (Active)
category
Proteins and Peptides
provider
Abbexa
reference
abx692702
tested applications
SDS-PAGE

Description

Mouse ACVR2B Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the extracellular domain (Met 1-Thr 134) of mouse ACVR2B (NP_031423.1) precursor was fused with the Fc region of human IgG1 at the C-terminus.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
ACVR2B
Host
HEK293 cells
Assay Type
Activity: Active
Sequence Fragment: Met1-Thr134
Tag: C-terminal His tag and Fc tag
Origin
Mouse
Observed MW
41 kDa
Expression
Recombinant
Purity
> 97% (SDS-PAGE)
Size 1
100 µg
Form
Lyophilized
Tested Applications
SDS-PAGE
Buffer
Lyophilized from sterile PBS, pH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Storage: Store lyophilized between -20 °C and -80°C.
Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months.
Shelf Life: 12 months.
Dry Ice
No
NCBI Accession
NP_031423.1
Alias
Activin receptor type IIB,ACTR-IIB
Background
Protein ACVR2B
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Endotoxin Level: < 1.0 EU per µg of the protein as determined by the LAL method.

Descripción

ACVR2B is another type II receptor involved in activin and myostatin signaling pathways. It phosphorylates type I receptors (e.g., ACVR1B) to activate SMAD-dependent signaling cascades. ACVR2B regulates processes like muscle growth, reproductive function, and embryonic development. Inhibition of ACVR2B has been explored as a therapeutic approach for muscle-wasting disorders, such as cachexia and muscular dystrophy. Mutations in ACVR2B can impair ligand-receptor interactions, leading to developmental defects.
Related Products
Pr22840
Recombinant Human ACVR2B
Ver Producto
Pr22841
Recombinant Human ACVR2B
Ver Producto
abx007082
Activin A Receptor Type 2B (ACVR2B) Antibody
ACVR2B Antibody is a Rabbit Polyclonal Antibody against ACVR2B.
Ver Producto