Mouse Alanine--TRNA Ligase, Cytoplasmic (AARS1) Protein
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Description
Alanine--tRNA Ligase, Cytoplasmic (AARS1) protein is a recombinant Mouse protein expressed in Insect.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Alanine--tRNA Ligase, Cytoplasmic (AARS1) |
| Host | Insect |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Asn968 Tag: C-terminal His tag |
| Origin | Mouse |
| Observed MW | 108.3 kDa |
| Expression | Recombinant |
| Purity | > 88% (SDS-PAGE) |
| Size 1 | 100 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: Sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10% glycerol. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | Q8BGQ7 |
| Alias | AARS1,AARS |
| Background | Protein AARS1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
Alanine-tRNA ligase, encoded by the genes AARS1 (cytoplasmic) and AARS2 (mitochondrial), is a member of the aminoacyl-tRNA synthetase (aaRS) family. These enzymes are crucial for protein synthesis, catalyzing the attachment of alanine to its corresponding tRNA (tRNA^Ala) in a process known as tRNA aminoacylation. This reaction is an essential step in the translation process, ensuring accurate incorporation of alanine into nascent polypeptides according to the genetic code.AARS1 functions in the cytoplasm and is involved in general protein synthesis and AARS2 operates in mitochondria, where it is critical for mitochondrial protein synthesis, essential for maintaining respiratory chain function.The genes encoding these enzymes are conserved across species, reflecting their indispensable role in cellular physiology. Mutations in these genes are associated with various diseases, including neurodegenerative disorders, mitochondrial dysfunction, and cancer.
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