Mouse Alcohol Dehydrogenase 1 (ADH1) Protein
234€ (10 µg)
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name
Mouse Alcohol Dehydrogenase 1 (ADH1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065212
tested applications
WB, SDS-PAGE
Description
Mouse Alcohol Dehydrogenase 1 (ADH1) is a recombinant Mouse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Alcohol Dehydrogenase 1 (ADH1) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Glu25-Asp228 Tag: N-terminal His tag |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 24.8 kDa Observed MW (SDS-PAGE): 22 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | P00329 |
| Gene ID | 11522 |
| Alias | ADH1 |
| Background | Protein ADH1A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 1000 µg/ml |
Descripción
ADH1A is a member of the alcohol dehydrogenase (ADH) family, specifically the alpha subunit of the class I ADH enzymes, which are expressed primarily in the liver and gastrointestinal tract. These enzymes catalyze the oxidation of alcohols to aldehydes, playing a central role in the metabolism of ethanol and other substrates such as retinol and hydroxysteroids. ADH1A contributes to the initial step of alcohol metabolism, enabling the conversion of ethanol into acetaldehyde, which is subsequently metabolized by aldehyde dehydrogenase. Its expression is critical for detoxification and energy production pathways. Genetic polymorphisms in ADH1A can affect enzyme activity, influencing an individual's alcohol tolerance and susceptibility to alcohol-related diseases such as liver cirrhosis and alcohol dependence. Beyond ethanol metabolism, ADH1A is also involved in retinoid metabolism, highlighting its broader role in cellular signaling and development.
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