Mouse Alcohol Dehydrogenase 8 (ADHFE1) ELISA Kit
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Description
Mouse Alcohol Dehydrogenase 8 (ADHFE1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Alcohol Dehydrogenase 8 (ADHFE1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Alcohol Dehydrogenase 8 (ADHFE1) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8R0N6 |
| Alias | HOT,ADH8,HMFT2263 |
| Background | Elisa Kits for: ADHFE1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
ADHFE1 is a unique alcohol dehydrogenase that utilizes iron as a cofactor, distinguishing it from other zinc-dependent ADH family members. This enzyme is expressed in the brain and liver, where it plays an important role in metabolizing hydroxyacid substrates such as 4-hydroxybutyrate, also known as gamma-hydroxybutyric acid (GHB). ADHFE1 is particularly involved in pathways related to the metabolism of hydroxy acids, contributing to energy production and cellular detoxification. Dysregulation or mutations in ADHFE1 can lead to the accumulation of hydroxyacid metabolites, which has been implicated in neurometabolic disorders and toxic encephalopathies. Its function in oxidative stress response and the regulation of hydroxyacid levels highlights its importance in maintaining brain and liver health. Although its direct role in ethanol metabolism is minimal, ADHFE1’s broader metabolic functions make it a significant enzyme in hydroxyacid processing and cellular energy dynamics.
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